How to beter acquire medical knowledge, if not from the theoretical basis and later supplemented by clinical case reports. This didactic approach seemed relevant and original in knowing, understanding and treating these pathologies. It was wanted to choose the most emblematic systemic pathologies, more precisely the most frequently encountered in an internal medicine and rheumatology service. The ability to establish a diagnosis, but also to exclude one, is in a balanced symbiosis, and the treatment is in a continuous dynamic. Some pathologies are serious, extremely serious, others less serious, but all have benefited from progress in how to precise and faster diagnose and treat these pathologies. Ancuta MIHAI, MD, PhD
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